Version 1 du 12 octobre 2020
Living SARS-CoV-2 in feces suggesting possible fecal-oral contamination
Julie Dergham, Jeremy Delerce, Marielle Bedotto, Bernard La Scola, Valérie Moal
After we observed a COVID-19 epidemic cluster associated with ruptured sewage pipe, we inoculated 106 stool samples from 46 patients to search for living SARS-CoV-2 and could isolate 2 strains. These 2 isolates were obtained from a unique patient with kidney transplantation under immunosuppressive therapy who was admitted for severe diarrhea. This report emphasizes that immune-compromised patients have probably massive multiplication of virus in the gastrointestinal tract and confirms possible fecal-oral transmission of SARS-CoV-2.